Curevac | Pandemic PACT Tracker

Key facts

Disease
COVID-19
Known Financial Commitments (USD)
$15,300,000
Funder
Coalition for Epidemic Preparedness Innovations (CEPI)
Principal Investigator
Pending
Research Location
Germany
Lead Research Institution
Curevac
Research Priority Alignment
N/A

Research Category
Vaccines research, development and implementation
Research Subcategory
Phase 1 clinical trial
Special Interest Tags
N/A
Study Type
Clinical
Clinical Trial Details
Clinical Trial, Phase I
Broad Policy Alignment
Pending
Age Group
Unspecified
Vulnerable Population
Unspecified
Occupations of Interest
Unspecified

Abstract

mRNA Full Length S stabilized (unmodified and codon optimized) Phase I safety and immunogenicity

Publicationslinked via Europe PMC

Last Updated:a day ago

View all publications at Europe PMC

Disordered regions in the IRE1α ER lumenal domain mediate its stress-induced clustering.

Inherited human RelB deficiency impairs innate and adaptive immunity to infection.

Authors
Le Voyer T, Maglorius Renkilaraj MRL, Moriya K, Pérez Lorenzo M, Nguyen T, Gao L, Rubin T, Cederholm A, Ogishi M, Arango-Franco CA, Béziat V, Lévy R, Migaud M, Rapaport F, Itan Y, Deenick EK, Cortese I, Lisco A, Boztug K, Abel L, Boisson-Dupuis S, Boisson B, Frosk P, Ma CS, Landegren N, Celmeli F, Casanova JL, Tangye SG, Puel A.
Publish Year
2024
Journal
Proceedings of the National Academy of Sciences of the United States of America
DOI
10.1073/pnas.2321794121

View at Europe PMC

Sex-specific high-sensitivity troponin T cut-points have similar safety but lower efficacy than overall cut-points in a multisite U.S. cohort.

Innate immune sensing of cell death in disease and therapeutics.

Exploring the feasibility and acceptability of community paramedicine programs in achieving vaccination equity: a qualitative study.

Recruitment of CXCR4+ type 1 innate lymphoid cells distinguishes sarcoidosis from other skin granulomatous diseases.

Integrating nutrition and culinary medicine into preclinical medical training.

Effectiveness of a nurse-led family empowerment program to improve the quality of life among pregnant adolescents: A randomized controlled trial.

SOX-5 Transcription Factor: a Novel Psoriatic Autoantigen Preferentially Found in Women.