Devising new methods to detect and visualize SARSCoV2 directly in infected human tissues
- Funded by UK Research and Innovation (UKRI)
- Total publications:0 publications
Grant number: C19-IUC-088
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Key facts
Disease
COVID-19Funder
UK Research and Innovation (UKRI)Principal Investigator
PendingResearch Location
United KingdomLead Research Institution
MRC Toxicology Unit at the University of CambridgeResearch Priority Alignment
N/A
Research Category
Pathogen: natural history, transmission and diagnostics
Research Subcategory
Immunity
Special Interest Tags
N/A
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Unspecified
Vulnerable Population
Unspecified
Occupations of Interest
Unspecified
Abstract
If immune cells (lymphocytes) are infected by this (SARS-CoV-2), then assumptions that patients previously infected are now immune may be incorrect. The project will devise new methods to detect and visualize SARS-CoV-2 directly in infected human tissues to determine which immune cells could be infected, which sub-class of two types of immune cells (T and B cells) are affected and which immune cells of the digestive tract may be affected. These methods will be able to confirm viral infection in deceased cases where a diagnosis was not made. _x005F_x005F_x005F_x005F_x005F_x005F_x005F_x000D_ _x005F_x005F_x005F_x005F_x005F_x005F_x005F_x000D_