Untersuchungen von molekularen SARS-CoV-2-Wirt-Interaktionen mit gezielten Knockouts und Pulldowns
- Funded by Bundesministerium für Bildung und Forschung [German Federal Ministry of Education and Research] (BMBF)
- Total publications:0 publications
Grant number: 01KI20393
Grant search
Key facts
Disease
COVID-19Start & end year
20202021Known Financial Commitments (USD)
$90,173.89Funder
Bundesministerium für Bildung und Forschung [German Federal Ministry of Education and Research] (BMBF)Principal Investigator
PendingResearch Location
GermanyLead Research Institution
Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (MDC)Research Priority Alignment
N/A
Research Category
Pathogen: natural history, transmission and diagnostics
Research Subcategory
Pathogen morphology, shedding & natural history
Special Interest Tags
N/A
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable
Abstract
discovery - This is a basic scientific research project on SARS-CoV-2. The aim of the project is to investigate in detail the mutual influences between the viruses and the metabolism of human host cells in a SARS-CoV-2 infection. Preliminary work has already identified certain ribonucleic acids (RNA) in the host cells, the expression of which is changed in the case of a SARS-CoV-2 infection. In the non-infected cell culture, this RNA should now be switched off (knockout) and the effects of an infection of the cells with the virus examined. Ultimately, possible new targets for pharmaceutical interventions against SARS-CoV-2 are to be found.