Covid-related changes in Taste Epithelium
- Funded by National Institutes of Health (NIH)
- Total publications:0 publications
Grant number: unknown
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Key facts
Disease
COVID-19Start & end year
20202021Known Financial Commitments (USD)
$191,384Funder
National Institutes of Health (NIH)Principal Investigator
PendingResearch Location
United States of America, GermanyLead Research Institution
University of Colorado DenverResearch Priority Alignment
N/A
Research Category
Clinical characterisation and management
Research Subcategory
Disease pathogenesis
Special Interest Tags
Data Management and Data Sharing
Study Type
Clinical
Clinical Trial Details
Not applicable
Broad Policy Alignment
Pending
Age Group
Unspecified
Vulnerable Population
Unspecified
Occupations of Interest
Unspecified
Abstract
PROJECT SUMMARYDisruption of the sense of taste is a common feature of COVID-19. The proposed supplement will investigatepotential histopathological changes in taste buds and the surrounding epithelium of the tongue in patients whohave lost their sense of taste during COVID-19. Biopsies of fungiform papillae will be obtained from a tastecenter in Germany which shall conduct psychophysical testing prior to sampling 4 fungiform papillae frompatients recovering from COVID-19 - either with or without taste loss. We will analyze these samplesmolecularly and histologically to test for presence of residual virus and for changes in taste bud number,morphology or cellular composition.