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Candidate therapeutics R&D - Arresting Coronavirus replication using a microRNA approach

  • Funded by UK Research and Innovation (UKRI)
  • Total publications:0 publications

Grant number: C19-IUC-037

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Key facts

  • Disease

    COVID-19

  • Funder

    UK Research and Innovation (UKRI)

  • Principal Investigator

    Prof. Chris Shaw

  • Research Location

    United Kingdom

  • Lead Research Institution

    UK Dementia Research Institute

  • Research Priority Alignment

    N/A

  • Research Category

    Therapeutics research, development and implementation

  • Research Subcategory

    Pre-clinical studies

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Arresting coronavirus replication using a microRNA approach, by devising and testing a microRNA/adenoviral vector-based strategy to treat COVID-19 infection by knocking down the orf1ab gene encoding the RNA-dependent RNA polymerase that SARS-CoV-2 uses to replicate.