SEQUENCE THE COMPLETE GENOME OF COVID-19 DIRECTLY AND AT LOW COST FROM PREPARED RNA SAMPLES FROM PATIENTS (CAPTURE-COV project)

Key facts

Disease
COVID-19
Funder
Institut Pasteur International Network (IPIN)
Principal Investigator
N/A
Research Location
N/A
Lead Research Institution
N/A
Research Priority Alignment
N/A

Research Category
Pathogen: natural history, transmission and diagnostics
Research Subcategory
Pathogen genomics, mutations and adaptations
Special Interest Tags
N/A
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable

Abstract

to be able to sequence the complete genome of Covid-19 directly and at low cost from prepared RNA samples from patients. We plan to implement a capture sequencing protocol targeting the SARS-CoV-2 genome using three commercial sets of probes in parallel. Results will be compared with a bioinformatics analysis pipeline and shared via publication (Biorxiv preprint followed by classical peer review).

Publicationslinked via Europe PMC

Last Updated:an hour ago

View all publications at Europe PMC

Electrocardiographic Assessment of National-Level Triathletes: Sinus Bradycardia and Other Electrocardiographic Abnormalities.

A mutant ASXL1-BAP1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia.

"Beyond the Finish Line" the Epidemiology of Injury and Illness in Professional Cycling: Insights from a Year-Long Prospective Study.

Calaspargase-Pegol-Mknl Combined with BCL-2 and MCL-1 Inhibition for Acute Myeloid Leukemia.

Enhanced Effect of Patient Room Disinfection Against Carbapenem-Resistant <i>Enterobacter cloacae</i> and Methicillin-Resistant <i>Staphylococcus aureus</i> Using UV-C Irradiation in Conjunction with UV-C Containment Unit.

Characterization of MSC Growth, Differentiation, and EV Production in CNF Hydrogels Under Static and Dynamic Cultures in Hypoxic and Normoxic Conditions.

Detection of Thrombosis Using Soluble C-Type Lectin-like Receptor-2 with D-Dimer Level and Platelet Count.

Newborn Screening for Spinal Muscular Atrophy: Variations in Practice and Early Management of Infants with Spinal Muscular Atrophy in the United States.

Challenges in Conducting Exercise Recovery Studies in Older Adults and Considerations for Future Research: Findings from a Nutritional Intervention Study.