URGENT DISCOVERY OF DRUG CANDIDATES THAT TARGET CORONAVIRUS SARS-COV-2 (DrugCandidates-SARS-CoV-2 project)
- Funded by Institut Pasteur International Network (IPIN)
- Total publications:219 publications
Grant number: Unknown
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Key facts
Disease
COVID-19Funder
Institut Pasteur International Network (IPIN)Principal Investigator
PendingResearch Location
N/ALead Research Institution
N/AResearch Priority Alignment
N/A
Research Category
Therapeutics research, development and implementation
Research Subcategory
Pre-clinical studies
Special Interest Tags
N/A
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable
Abstract
rapidly provide drug candidates to treat victims of Covid-19. We will do this by applying our cutting-edge technologies and libraries to screen for viable active compounds that kill coronavirus. The strategy will employ phenotype screens (FPDD) that test for coronavirus inhibition using mouse (MHV-59) and human (OC43) virus as models for fast compound screening in cell culture. Direct-acting antivirals will also be sought via target-based screening (FBDD) as inhibitors of essential viral proteins of SARS-CoV-2.
Publicationslinked via Europe PMC
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