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COntrol of COVID-19 iN Hospitals (COCON-study)

  • Funded by Netherlands Organisation for Health Research and Development (ZonMW)
  • Total publications:0 publications

Grant number: 1.01501E+13

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2020
    2021

  • Known Financial Commitments (USD)

    $690,099.4

  • Funder

    Netherlands Organisation for Health Research and Development (ZonMW)

  • Principal Investigator

    Prof dr and Dr J Kand MFQ Kluytmans

  • Research Location

    Netherlands

  • Lead Research Institution

    Utrecht University Medical Centre

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Adults (18 and older)

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Health Personnel

Abstract

This study will evaluate the sero-epidemiology in healthcare workers (HCWs) in Dutch hospitals in regions with varying incidence of COVID-19. Study design: Cross-sectional study with prospective follow-up during 3 months. Study population: 2000 HCWs employed in one of the participating hospitals. Main study endpoints: Primary endpoint: seroprevalence of SARS-CoV-2 neutralising antibodies. Secondary endpoints: seroprevalence of SARS-CoV-2 total antibodies, cumulative incidence of seroconversion for SARS-CoV-2 (neutralising) antibodies, sqRT- PCR-confirmed SARS-CoV-2 infection, virus culture-confirmed infection, self-reported symptoms suspected for COVID-19, (unplanned) absenteeism, hospital admission and death.